Successful treatment of recalcitrant cutaneous sarcoidosis with fumaric acid esters
نویسندگان
چکیده
منابع مشابه
Successful treatment of recalcitrant cutaneous sarcoidosis with fumaric acid esters
BACKGROUND Sarcoidosis is a multisystem disease of unknown origin characterized by the formation of noncaseating granulomas, in particular in the lungs, lymph nodes, eyes, and skin. Systemic treatment for cutaneous sarcoidosis can be used for large disfiguring lesions, generalized involvement, or recalcitrant lesions that did not respond to topical therapy. CASE PRESENTATIONS We report three ...
متن کاملTreatment of disseminated granuloma annulare with fumaric acid esters
BACKGROUND Granuloma annulare is a granulomatous disease of unknown etiology. Various therapies have been tried in disseminated granuloma annulare (DGA), including corticosteroids, several variants of psoralen plus ultraviolet-A radiation, ultraviolet- A1 radiation, systemic retinoids, and dapsone, with variable success. We report a patient with recalcitrant DGA who was treated with fumaric aci...
متن کاملUse of fumaric acid esters in psoriasis.
Fumaric acid esters (FAE) are chemical compounds derived from the unsaturated dicarbonic acid fumaric acid. The usage of FAEs in treatment of psoriasis was introduced in the late 1950's. In the 1980s more standardized oral preparations of FAEs were developed containing dimethylfumarate (DMF) and salts of monoethylfumarate (MEF) as main compounds. In 1994, Fumaderm an enteric-coated tablet conta...
متن کاملSuccessful treatment of cutaneous sarcoidosis using topical photodynamic therapy.
A 67-year-old woman had a 17-year history of increasing numbers of asymptomatic but disfiguring red-brown, flat papules on the extremities. She was otherwise well and had no pulmonary or systemic symptoms. Seven years ago, the patient was referred to our department, and the diagnosis of cutaneous sarcoidosis (small nodular type) was repeatedly confirmed by skin biopsy results. The physical exam...
متن کاملIn vitro pharmacokinetics of anti-psoriatic fumaric acid esters
BACKGROUND Psoriasis is a chronic inflammatory skin disease that can be successfully treated with a mixture of fumaric acid esters (FAE) formulated as enteric-coated tablets for oral use. These tablets consist of dimethylfumarate (DMF) and salts of monoethylfumarate (MEF) and its main bioactive metabolite is monomethylfumarate (MMF). Little is known about the pharmacokinetics of these FAE. The ...
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ژورنال
عنوان ژورنال: BMC Dermatology
سال: 2002
ISSN: 1471-5945
DOI: 10.1186/1471-5945-2-15